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ANNAPOLIS, Md. (AP) - A federal appeals court has struck down Maryland's first-in-the-nation law against pharmaceutical price gouging.

A divided three-judge panel of the 4th U.S. Circuit Court of Appeals ruled Friday the law is unconstitutional. The ruling says that's because it regulates transactions that take place outside of Maryland and burdens interstate commerce in prescription drugs.

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There were a host of new laws that went into effect this weekend in Maryland ranging from opioids and health care to marijuana and domestic abuse.

One measure prohibits price gouging by makers and distributors for the sale of essential generic drugs.

Meanwhile, a conviction for marijuana possession can be expunged.

The Salisbury Daily Times reports that another law calls for the reduction of the prison population and cutting recidivism with rehabilitation efforts for certain nonviolent crimes.

But gang related offenses will be toughened.

BALTIMORE (AP) - A Maryland measure that would empower the state's attorney general to take action to stop pharmaceutical price gouging is scheduled for a hearing in federal court.

A motions hearing is set for U.S. District Court in Baltimore on Thursday.

A group representing manufacturers of generic prescription drugs has filed a lawsuit against the state. The Association for Accessible Medicines says the law, which takes effect Oct. 1, is an "unconstitutional overreach." They say it will create instability in the market for generic drugs.